Peyronie’s Disease Caused by Penile Injections for the Treatment of ED – EDEX, Trimix, Prostaglandin

by Alex Shteynshlyuger MD


If you have any questions, to schedule a consultation, please contact us or call/text: 1-646-663-4050.

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We offer affordable prices with or without insurance.


Peyronie’s Disease after Penile Injections: What You Need to Know

Penile injections with medications such as Edex, Caverject, and Trimix is an effective treatment for men with erectile dysfunction.

15 to 20% of men develop signs of Peyronie’s disease after prolonged use of penile injections for the treatment of erectile dysfunction. Common signs of Peyronie’s disease include the curved penis, Peyronie’s plaque, hourglass appearance, and penile shortening.

The needles used for penile injections are very small and cause minimal damage or scar formation. However, over time and repeated use, scarring may develop in the penis. Men with erectile dysfunction are likely predisposed to Peyronie’s disease due to impaired vascular supply to the penis. Adequate vascular supply is essential to self-healing of tissues in the body; poor blood flow to the penis in men with ED likely increased the risk of Peyronie’s disease.

Most men who use penile injections do so because oral medications such as tadalafil (Cialis) and sildenafil (Viagra) do not work sufficiently well. In this situation, the only options available are to proceed with a penile implant or to try penile injections.  There is no significant downside from using injections in this situation even if it results in the development of Peyronie’s disease.

If Peyronie’s disease is severe enough to require surgical treatment they would undergo penile implant surgery that they would have otherwise needed if they chose not to use penile injections.

Did you know?  Dr. Shteynshlyuger has performed over 1,000 penile surgeries including penile implants, correction of Peyronie’s disease, circumcisions, circumcision revisions, frenuloplasty, and congenital penile curvature.  He performs 150-200 penile surgeries a year.

Where to Get Peyronie’s Treatment in NYC?

At New York Urology Specialists, we offer treatment for men with Peyronie’s disease. 

Call/text today: 1-646-663-4050 or make an appointment online.  

We treat sexual and erection problems and Peyronie’s disease.  We offer comprehensive STD testing for infections.  We treat penile problems in men, including phimosis, balanitis, penile irritation, and penile redness. We perform a no-scalpel vasectomy, vasectomy reversal, cosmetic circumcision, circumcision revision, penile frenuloplasty. We offer confidential appointments.

Our appointment costs are affordable with or without insuranceLow-cost Viagra (sildenafil) and Cialis (tadalafil) are available to our patients.  We offer free insurance verification.

Read Real Stories of Men who Underwent Treatment for Peyronie’s Disease at New York Urology Specialists.

Read RealStories: 67-year-old man with dorsal curvature and ED after the use of Trimix injections.

Read RealStories: 58-year-old man with penile shortening and narrowing after prostate cancer treatment treated with a penile implant and grafting.

Read RealStories: 47-year-old man with penile shortening, narrowing and curvature treated with Xiaflex and plaque excision

Cost of Treatment and Insurance

At New York Urology Specialists, we offer affordable treatment for men. Our prices are low for patients without insurance and for those who have high insurance copays, high deductibles, or insurance plans that do not cover treatment costs. 

We accept many health insurance plans.  We would be happy to verify your eligibility and benefits and to provide you with detailed information on your health plan’s coverage.  Financing options and credit options are available to help you pay for medical care.

Why Choose New York Urology Specialists for Treatment of Peyronie’s Disease?

  • All treatment is performed by a board-certified urologist experienced in treating men with symptoms of Peyronie’s disease, including penile curvature, narrowing of the penis, shortening of the penis, pain in the penis, and ED.  
  • We are one of the few practices in the region to offer a full range of options for treatment of Peyronie’s disease, sexual and erection problems in men.
  • We offer diagnostic testing in our office, which avoids hospital costs.
  • Extensive experience: Thousands of men have been treated successfully using medical therapy (Xiaflex, Verapamil injections, Interferon), shockwave therapy for penile pain, penile plication, plaque excision and grafting, and penile implant surgery.
  • Confidential and Understanding Care. We understand that most of our patients desire privacy.  We see patients with a variety of urological problems. Your reason for visiting us is entirely confidential.
  • We offer diagnostic testing in our office, which avoids hospital costs.
  • We are conveniently located within a 30-60 minute commute to men who are seeking ED treatment in Manhattan, Brooklyn, Queens, Staten Island, Westchester, Long Island, Bronx, and New Jersey.

What does Peyronie’s Penile Curvature Look Like?

You can find before and after treatment images in our image gallery.

Scheduling Appointments for Peyronie’s Treatment at New York Urology Specialists


If you have any questions, to schedule a consultation, please contact us or call/text: 1-646-663-4050.

We have excellent reviews from patients and their partners.  Information for out-of-state and international patients.  

We offer affordable prices with or without insurance.

Dr. Alex Shteynshlyuger is a board-certified urologist and specialist in the treatment of sexual problems in men including Peyronie’s disease and erectile dysfunction.  He is one of the few urologists who offers a full range of treatment options for Peyronie’s disease and ED.  He has successfully treated thousands of men with sexual problems.

When it comes to the treatment of Peyronie’s disease – New York Urology Specialists are a step ahead.  Better Science Means Better Care.   Dr. Alex Shteynshlyuger is a specialist in treating erection and penis problems using the latest scientific and medical breakthroughs.

Find out our office hours or directions to our office


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Peyronies Disease and ED Are Treatable in Nearly Every Man

Excellence-Urology_Care-banner2At New York Urology Specialists, our urologists are specially trained in the evaluation and treatment of Peyronie’s disease and erectile dysfunction.  We understand the challenges that Peyronie’s disease and ED create for our patients, their relationships, and their self-esteem.  We help you find a treatment for Peyronie’s disease that fits your needs, lifestyle, and your preferences.

Urologists are doctors specializing in the treatment of men with sexual problems including Peyronie’s disease and erectile dysfunction. By virtue of our experience and skill, we are able to offer an effective treatment option for nearly every man who desires an effective treatment for ED.  We offer medical and surgical treatment for Peyronie’s disease and erectile dysfunction.

We Treat Some of the Most Complex Peyronie’s Problems and Men’s Health Problems Including:

Schedule an Appointment with Dr. Shteynshlyuger:

Call/text today: 1-646-663-4050 or make an appointment online

Dr. Alex Shteynshlyuger is a fellowship-trained, board-certified urologist with expertise in the evaluation and treatment of sexual and erection problems in men using modern, effective, and proven treatment methods.  We offer inflatable penile implant, shockwave therapy for ED, and treatment for Peyronie’s disease.

He is highly recommended by top primary care physicians in the New York area. If you or someone you know has been experiencing urological symptoms, make an appointment to take advantage of Dr. Shteynshlyuger’s expert advice. Please feel free to contact us with any questions.


If you have any questions, to schedule a consultation, please contact us or call/text: 1-646-663-4050.

We have excellent reviews from patients and their partners.  Information for out-of-state and international patients.  

We offer affordable prices with or without insurance. 

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