Xiaflex for Peyronie’s Disease in New York
If you have any questions, to schedule a consultation, please contact us or call/text: 1-646-663-4050.
We have excellent reviews from patients and their partners. Information for out-of-state and international patients.
We offer affordable prices with or without insurance.
What is Xiaflex?
Xiaflex is a brand name for collagenase (USA; in Europe, the brand name is Xiapex), a naturally occurring enzyme that is involved in tissue repair. XIAFLEX is the first FDA-approved medication for the treatment of Peyronie’s disease. It is effective for the treatment of moderate to severe Peyronie’s Disease.
Xiaflex is a naturally occurring enzyme called collagenase. Collagenase breaks down collagen, which is a protein that is present in scar tissue. By breaking scar tissue, Xiaflex treats the cause of Peyronie’s disease directly.
Who is a Candidate for Xiaflex/Xiapex Treatment?
FDA approved XIAFLEX for use in men with at least 30-degree penile curvature and a palpable plaque (which is necessary to inject into it).
Read more about Xiaflex treatment for Peyronie’s disease and our patient selection criteria for Xiaflex. Men should be able to obtain a good erection on their own or with the help of medications. Men should NOT have significant hourglass narrowing of the penis.
Where to Get Peyronie’s Treatment with Xiaflex in NYC?
At New York Urology Specialists, we offer treatment for men with penis problems, including Xiaflex administration for Peyronie’s disease.
Call/text today: 1-646-663-4050 or make an appointment online.
We treat sexual and erection problems and Peyronie’s disease. We offer comprehensive STD testing for infections. We treat penile problems in men, including phimosis, balanitis, penile irritation, and penile redness. We perform a no-scalpel vasectomy, vasectomy reversal, cosmetic circumcision, circumcision revision, and penile frenuloplasty. We offer confidential appointments.
Our appointment costs are affordable with or without insurance. Low-cost medications are available to our patients. We offer free insurance verification.
Read Real Stories of Men who Underwent Treatment for Peyronie’s Disease at New York Urology Specialists.
Read RealStories: Penile pain in a 51-year old adult male with curvature to the left and up treated with Xiaflex and penile traction.
Read RealStories: 63-year-old man with Peyronies and ED treated with Xiaflex.
Read RealStories: 75-year-old man with penile narrowing and curvature treated with interferon
Read RealStories: 47-year-old man with penile shortening, narrowing and curvature treated with Xiaflex and plaque excision
What is the Procedure for Getting Treated with Xiaflex for Peyronie’s Disease?
Initial evaluation requires 1-3 visits to determine if you’re a good candidate for Xiaflex (have a good chance of benefiting from it). Usually, you would need a consultation during which we would need to administer an injection to create an artificial erection so that we can properly evaluate the plaque and see if you’re a good candidate for Xiaflex or any other treatments. Penile Doppler ultrasound is performed.
If you are a candidate for Xiaflex and decide to proceed, we will schedule you for treatment with Xiaflex. Read more about costs and insurance coverage. Each treatment cycle is approximately 7 days. Injection on day 1; then another injection on day 2-3; then penile remodeling 3-4 days later.
You then are taught to do remodeling by yourself for 7 weeks at home; then a 2nd cycle is given again over a period of 1 week, followed by a 7-week period of self-remodeling for 4 cycles total. So each cycle is spread by 7 weeks from the next one. If your curvature becomes <15 degrees, then we stop it. The maximum we can do is 4 cycles. For patients with multiple plaques, if there is a good response, additional treatment can be tried.
Costs of Xiaflex are usually covered by insurance in the USA. There are some insurance companies outside the US that may pay for treatment in the US with Xiaflex. Financial support programs for patients without insurance and with a high deductible are available.
How Effective is Xiaflex for the treatment of Peyronie’s Disease?
Randomized controlled studies show that Xiaflex is one of the most effective medications for the treatment of Peyronie’s disease in men. Overall around 60% of men who are ideal candidates for Xiaflex experience some benefit from treatment with Xiaflex. Success rates are lower for patients who are not ideal candidates for Xiaflex.
How is Xiaflex Administered?
Xiaflex is administered by injecting the active medication into the Peyronie’s plaque in the penis. Usually, the administration is done in combination with penile plaque modeling. Read our detailed explanation of the treatment approach and treatment schedule.
Pain and Anesthetic Expectations:
Xiaflex injection involves a needle injection – usually, there is some discomfort, but it is fairly tolerable for a minute or so that it takes to inject the medication. There is no general anesthesia (you’re fully awake), but we can give a local anesthetic if you wish. The patient can walk in and walk out of the office. The pain is what you would expect from an injection. Patients cannot have sex for 4 weeks after each injection due to the risk of penile fracture.
Xiaflex Success Rates
Success rates vary, but studies demonstrate an average 34% improvement in the curvature (or 17-degree decrease from baseline curvature). 60% of men getting Xiaflex experienced improvement compared to 30% with placebo. Our experience with Xiaflex suggests that the success rate depends on the patient’s disease severity.
Many patients with Peyronie’s are not ideal candidates for Xiaflex due to plaque calcification. Patients who are not ideal candidates for Xiaflex typically experience less benefit from Xiaflex. It is important to understand that not everyone experiences improvement after treatment with Xiaflex. On the other hand, some men experience a dramatic improvement in their curvature. Xiaflex does not treat the hourglass appearance.
Xiaflex Treatment Schedule
Xiaflex is administered in 4 cycles, each cycle is one week long, followed by 7 weeks of at-home penile self-remodeling. Overall, it takes close to 6 months to administer the full cycle. Patients who prefer faster results may consider other treatment options. Alternative administration protocols are also possible.
At New York Urology Specialists, our Xiaflex treatment schedule includes an initial evaluation to determine if Xiaflex is an appropriate option for the individual man who comes to us with Peyronie’s disease. Some men may be better served with other treatment options for Peyronie’s disease. International patients may undergo initial evaluation in their home country from a local urologist experienced in the treatment of Peyronie’s disease.
What are the Risks of Xiaflex?
Randomized controlled trials revealed that there are a number of risks associated with the injection of Xiaflex in the penile plaque. These include bruising, hematoma, penile swelling, penile pain as well as a number of other common side effects. A significant and concerning side effect that has been noted in less than 1% of men who received Xiaflex is a rupture of the corpora albuginea. This is a major reason that the FDA has approved Xiaflex with the requirement for careful administration by properly trained and experienced urologists.
- Penile hematoma (bruising, hematoma): 66% – usually minor goes away after 1-2 weeks
- Severe penile hematoma: 6% goes away after 1-2 weeks
- Penile Swelling: 55% goes away after 1-2 weeks
- Penile Pain: 45%
- Painful erection: 3%
- “Popping sounds or cracking sounds“: 13%
Corporal rupture: 0.5% (occurs typically within the first 2 weeks after injection; for this reason, no sex is allowed for 4 weeks after each injection).
Who is a Candidate for Xiaflex?
Not every patient with Peyronie’s disease is a candidate for Xiaflex. Currently, men with Peyronie’s with greater than 30-degree angle are candidates. Men should be able to obtain good erections to qualify.
The plaque cannot be close to the urethra; however, studies show that some men with ventral penile curvature can be safely treated. The indications for using Xiaflex is curvature greater than 30 degrees, preferably with minimal calcification. Health insurance only covers the cost of treatment for lateral and dorsal penile curvature.
Because the medication works to break up proteins, it may not work well (or at all) in heavily calcified plaques (these were excluded from studies). The plaque also needs to be palpable so that we know we are injecting in the right space. There are some additional criteria. Read about our qualifications for Xiaflex treatment.
Costs and Insurance Coverage for Xiaflex (Peyronie’s Disease)
The cost of medication is high. The good news for men with Peyronie’s disease is that most insurances provide coverage for Xiaflex, including Medicare, UnitedHealthcare, Aetna, Blue Cross plans, and many others. We work through the Xiaflex Experience program to get your insurance to cover the costs of treatment. Insurance coverage may also be available for some of our international patients. Read more about costs and insurance coverage for Xiaflex.
Patients with no insurance or high deductibles may be well served by other cost-effective treatment options for Peyronie’s disease.
Certified Prescriber of Xiaflex for Peyronie’s Disease in NYC
New York Urology Specialists is one of the First Practices to use Xiaflex for Peyronie’s disease.
New York Urology Specialists is one of the first and few specialized urology practices in the New York Metropolitan area to become REMS-certified for prescribing Xiaflex (Collagenase) to men with moderate-to-severe Peyronie’s Disease.
Dr. Alex Shteynshlyuger is experienced in the treatment of Peyronie’s disease. New York Urology Specialists achieved FDA-mandated REMS certification in December 2013, one of the first practices in New York City and the tri-state area to achieve this certification. REMS Healthcare Provider Enrollment ID for New York Urology Specialists is 3000040.
Xiaflex is the first FDA-approved treatment for Peyronie’s disease, which gained FDA approval in December 2013 based on efficacy data from randomized controlled trials.
Experienced urologists at New York Urology Specialists have treated hundreds of patients with Peyronie’s disease. We offer minimally invasive medical as well as surgical treatment options for Peyronie’s disease and erectile dysfunction.
Did you know? Dr. Shteynshlyuger has performed over 1,000 penile surgeries, including penile implants, correction of Peyronie’s disease, circumcisions, circumcision revisions, frenuloplasty, and congenital penile curvature. He performs 150-200 penile surgeries a year.
Cost of Treatment and Insurance
At New York Urology Specialists, we offer affordable treatment for men. Our prices are low for patients without insurance and for those who have high insurance copays, high deductibles, or insurance plans that do not cover treatment costs.
We accept many health insurance plans. We would be happy to verify your eligibility and benefits and to provide you with detailed information on your health plan’s coverage. Financing options and credit options are available to help you pay for medical care.
Why Choose New York Urology Specialists for Treatment of Peyronie’s Disease?
- All treatment is performed by a board-certified urologist experienced in treating men with symptoms of Peyronie’s disease, including penile curvature, narrowing of the penis, shortening of the penis, pain in the penis, and ED.
- We are one of the few practices in the region to offer a full range of options for treatment of Peyronie’s disease, sexual and erection problems in men.
- We offer diagnostic testing in our office, which avoids hospital costs.
- Extensive experience: Thousands of men have been treated successfully using medical therapy (Xiaflex, Verapamil injections, Interferon), shockwave therapy for penile pain, penile plication, plaque excision and grafting, and penile implant surgery.
- Confidential and Understanding Care. We understand that most of our patients desire privacy. We see patients with a variety of urological problems. Your reason for visiting us is entirely confidential.
- We offer diagnostic testing in our office, which avoids hospital costs.
- We are conveniently located within a 30-60 minute commute to men who are seeking ED treatment in Manhattan, Brooklyn, Queens, Staten Island, Westchester, Long Island, Bronx, and New Jersey.
What does Peyronie’s Penile Curvature Look Like?
You can find before and after treatment images in our image gallery.
Scheduling Appointments for Peyronie’s Treatment at New York Urology Specialists
If you have any questions, to schedule a consultation, please contact us or call/text: 1-646-663-4050.
We have excellent reviews from patients and their partners. Information for out-of-state and international patients.
We offer affordable prices with or without insurance.
Dr. Alex Shteynshlyuger is a board-certified urologist and specialist in the treatment of sexual problems in men, including Peyronie’s disease and erectile dysfunction. He is one of the few urologists who offer a full range of treatment options for Peyronie’s disease and ED. He has successfully treated thousands of men with sexual problems.
Peyronies Disease and ED Are Treatable in Nearly Every Man
At New York Urology Specialists, our urologists are specially trained in the evaluation and treatment of Peyronie’s disease and erectile dysfunction. We understand the challenges that Peyronie’s disease and ED create for our patients, their relationships, and their self-esteem. We help you find a treatment for Peyronie’s disease that fits your needs, lifestyle, and preferences.
Urologists are doctors specializing in the treatment of men with sexual problems, including Peyronie’s disease and erectile dysfunction. By virtue of our experience and skill, we are able to offer an effective treatment option for nearly every man who desires an effective treatment for ED. We offer medical and surgical treatment for Peyronie’s disease and erectile dysfunction.
We Treat Some of the Most Complex Peyronie’s Problems and Men’s health problems, including:
- Hourglass narrowing of the penis
- Shortening of the penis and loss of penile length
- Penis curvature with worsening erections
- Peyronies disease in men with diabetes and weak erections in men with diabetes.
- Peyronie’s disease and erectile dysfunction in men with prostate cancer after radical prostatectomy
- Erectile dysfunction in men with Peyronie’s disease
- Erectile dysfunction in men for whom medications do not work.
- Premature Ejaculation
- Frequent urination
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Schedule an Appointment with Dr. Shteynshlyuger:If you have any questions, to schedule a consultation, please contact us or call/text: 1-646-663-4050.
We have excellent reviews from patients and their partners. Information for out-of-state and international patients.
We offer affordable prices with or without insurance.
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