Peyronie’s Plaque: Lump in the Penis.
What is Peyronie’s Plaque?
Peyronie’s plaque refers to a formation of scar tissue often with calcification within the penis. Typically, the scar tissue is located in the wall that holds the penis together, called tunica albuginea of the penis.
Oftentimes, one can feel a small mass or ‘lump‘ that corresponds to Peyronie’s plaque. Sometimes there is no palpable lump in the penis and the diagnosis of Peyronie’s disease is suggested by pain in the penis, penile curvature or narrowing of the penis.
It is not uncommon for more than one penile plaque or lump to be found in the penis in men with Peyronie’s disease.
Not all penile lumps are Peyronie’s plaques. Other causes of lumps in the penis may be penile cancer, dystrophic calcification, and other conditions. It is important to see an urologist for evaluation.
Penile ultrasound can be performed to visualize penile plaque.
What Is The Cause Of Penile Plaque?
The reasons for the formation of penile plaque leading to Peyronie’s disease are complex. Scar formation involves the interaction of genetics, modifiable risk factors such as diabetes and penile trauma.
Some men with Peyronie’s disease have a history of penile pain during sex and subsequently notice penile curvature a few weeks or a few months later. Other men do not recall any history of trauma.
Penile trauma may be microscopic and not obviously painful or noticeable to the patient. The abnormal healing process that usually leads to resolution of the scar tissue, causes abnormal scar formation which asymmetrically shortens and contracts penile tissue. This leads to penile curvature.
Some men are genetically predisposed to Peyronie’s disease and also have Dupuytren’s contracture (scar tissue on the palms of the hands and fingers causing curvature / difficulty opening up the palm or straightening the fingers).
Occasionally, men with particular medical conditions such as diabetes, priapism, and kidney failure are predisposed to forming calcified plaques in the body. When this process occurs in the penis it can lead to Peyronie’s disease.
Does Everyone With Peyronie’s Disease Have a Penile Plaque?
Many patients with Peyronie’s disease have a palpable lump in their penis called “Peyronie’s plaque“. Some men with Peyronie’s disease do not have a palpable Peyronie’s plaque. Sometimes but not always Peyronie’s plaque can be seen on ultrasound of the penis.
A man without a palpable Peyronie’s plaque can still have Peyronie’s disease if they have any of the other symptoms that commonly occur with Peyronie’s disease: bent penis, pain in the penis or penile narrowing.
What are the Symptoms of Penile Plaque
- Penile Shortening
- Narrowing of the Penis on one side or circumferentially
- Penile curvature
- Erectile Dysfunction (difficulty obtaining and maintaining erections)
- Erection Softness
What’s the Treatment for Scar Tissue in the Penis?
Treatment options for penile plaque depend on the severity of symptoms and the quality of erections. In general treatment options include:
- oral medications
- Injectable medications into the Peyronie’s plaque. (Xiaflex, verapamil, interferon)
- Plaque incision/excision with or without grafting; penile prosthesis
- Penile plication
- Penile prosthesis with penile remodeling/plication/plaque incision/excision/grafting.
- Observation, if there are no symptoms or the symptoms, are mild and the disease process is stable.
We offer affordable, highest-quality urology care.