Verapamil Injections for Treatment of Peyronie’s Disease in NYC

by Alex Shteynshlyuger MD

If you have any questions, to schedule a consultation or if you need a second opinion, please contact us or call 1-(646) 663-4050.

Dr. Alex Shteynshlyuger is a board-certified urologist in NYC who specializes in treating men with Peyronie’s disease.

What is Verapamil?

Verapamil Injections Peyronie'sVerapamil is a medication from a class of medications called calcium channel blockers.   It is useful in many conditions including for treatment of high blood pressure.  It was also found to be useful in treating men with Peyronie’s disease.

Is All Verapamil Created Equal?

Only verapamil injected directly into Peyronie’s plaque has been shown to be effective in the treatment of Peyronie’s disease. Oral verapamil pills are not effective for treatment of Peyronie’s disease.  Verapamil in cream form is not effective for treatment of Peyronie’s disease.

Intra-lesional Verapamil Injections Have an Excellent Record of Effectiveness and Safety.

Verapamil injections have been used for more than 30 years to treat men with Peyronie’s disease. The injections are nearly painless (we administer local pain medication prior to giving injections in the penis).

Verapamil is inexpensive and has good efficacy with at least 20-30% of men experiencing significant improvement in symptoms and/or curvature.

We usually advise using verapamil injections in combination with penile traction therapy and oral therapy.

How Often Are Verapamil Injections Given?

Typically, the course of treatment with verapamil injections is 6 injections spaced two weeks apart.  The entire treatment takes about 12 weeks.  It is safe to skip a week or two and resume the next dose of the medication if needed (vacations/busy, etc).

If after the first course of Verapamil significant improvement is noted, the course of treatment can be repeated.

If there is no benefit after 6 injections, additional injections are unlikely to help and a different treatment approach should be tried.

Risks and Side Effects of Verapamil Injections

Verapamil injections are very safe when administered by an experienced urologist. Usually, a local anesthetic is given and the injection of verapamil is usually painless.  Slight hematoma (bleeding) can occur occasionally but goes away within a week or two.

Verapamil Injections vs Topical Verapamil Cream

Topical verapamil has no benefit in the treatment of men with Peyronie’s disease.  To be effective, verapamil needs to be injected directly into Peyronie’s plaque.

Treatment Options When Verapamil Injections Do Not Help

If verapamil injections do not provide sufficient benefit, Xiaflex injections, as well as plaque incision/grafting or penile implant, offer effective treatment for Peyronie’s.

If you have any questions, to schedule a consultation or if you need a second opinion, please contact us or call 1-(646) 663-4050.