Penis Injection Therapy for Treatment of ED in Men in NYC

by Dr. Alex Shteynshlyuger 

If you have any questions, to schedule a consultation, please contact us or call/text: 1-646-663-5211.

We have excellent reviews from patients and their partners.  Information for out-of-state and international patients.  Find out our office hours or directions to our office

We offer affordable appointment prices with or without insurance.  Low-cost Viagra (sildenafil) and Cialis (tadalafil) are available to our patients.

At New York Urology Specialists we have successfully treated thousands of men who previously suffered from problems with erections. All treatment is confidential.

Penile Injection Treatment for Erectile Dysfunction: What You Need to Know

When oral pills such as Viagra, Cialis, and Levitra do not work well, injectable medications can be used to directly deliver medications that improve blood flow to the penis and allow men to get excellent erections.  These medications are self-injected directly into the penis at home, typically 10-15 minutes before sex.

Penile injection therapy results in high satisfaction rates among men for whom oral medications do not work well.  Men who experience severe side effects from oral medications, such as sildenafil and tadalafil, can use penile injections to get good erections.

The part of the penis that creates erections is called “corpus cavernosum”. Injectable medications used in the treatment of ED are injected directly into the part of the penis where erections occur.

Penile Injections for ED in NYC: How to Get Started

At New York Urology Specialists, we offer penile injection therapy with Trimix, Quadmix, Edex and other effective preparations for the treatment of erectile dysfunction.

Schedule an appointment for an evaluation to see if you are a good candidate for penile injection treatment for ED.  At New York Urology Specialists you may save thousands of dollars by learning facts about other penile injections such as “platelet injections” that are offered for ED.

Benefits of Penile Injections For Treatment of Erectile Dysfunction.

Erectile dysfunction treatment with injections offers a number of benefits to men.  Penis injections allow many men to obtain excellent erection quality (hardness) when oral pills and supplements do not work as well.  Using injection therapy for erectile dysfunction can also allow men to maintain erections for a prolonged period of time without losing it even after ejaculation.  This is helpful to men with premature ejaculation.

Many men are worried about the pain of self-injecting medications in the penis. Fortunately, using tiny needles, penile injections are nearly painless.

Treatment with Penis Injection Therapy

At New York Urology Specialists, we offer therapy with penile injection therapy as one of the many options for men who experience difficulty obtaining erections that are sufficient for intercourse.  Our procedure for men who are interested in penile injections for ED:

  • Schedule an initial appointment for evaluation; necessary tests and blood work are ordered
  • Penile Doppler ultrasound is performed to evaluate the cause of ED and a test injection is given
  • Another test injection may be necessary to select a correct dose of medications.
  • If a patient wants to use penile injections at home for treatment of ED, the patient can order penile injections to be used at home.  The patient will be taught how to self-inject correctly.

Our experienced urologists have treated hundreds of men with penile injection therapy.

Penis Injections for Treatment for Weak Erections

A few different medications are available to choose from that can be injected into the penis to produce a good erection.  We use our extensive experience and patient preferences to determine the most appropriate medication for each patient.

Medications used for penile injections act on the blood vessels to improve blood flow to the penis.  Injectable medications used for ED treatment include in order of potency:

Each medication (Prostaglandin, Bimix, Trimix, Quadmix) is available in multiple concentrations (strengths); medications obtained from different pharmacies are not interchangeable.

Getting Penile Injections

Medications used for penile injections require a prescription. At New York Urology Specialists we require a full evaluation before penile injections are prescribed.  It is important that you fully understand all options available for the treatment of ED as well as the risks and benefits of penile injection therapy for impotence.

Before we prescribe penile injections, the correct medication and the correct dose need to be selected. In general, when choosing medication our goal is to select the medication and dose to provide an excellent erection that does not last more than 1 hour (to avoid the risk of priapism).  This is typically performed during a penile Doppler ultrasound study to evaluate the severity and cause of erection problems.

Retail pharmacies such as CVS, Walgreens and others do not carry Bimix, Trimix and Quadmix; these need to be custom-ordered from special pharmacies. At New York Urology Specialists we only use FDA-certified pharmacies.  Retail pharmacies carry EDEX and Caverject but tend to be very expensive compared to generic prostaglandin

For the convenience of our patients, we work with pharmacies that offer less expensive injectable medications that require refrigeration; we also work with pharmacies that offer more expensive medications that do not require refrigeration which is convenient for men who travel extensively.

Side Effects of Penile Injection Therapy

Injectable medications for ED are highly effective but they are associated with some side effects which do not occur with oral medications.  

A small number of men may experience pain after penile injections if the erections are too strong. Lowering the dose of medications usually solves this problem. 

When prostaglandin is injected alone, 30-40% of men report pain which occurs when the medication starts working, typically 10-15 minutes after injection This pain is rare with Trimix and does not occur with Bimix.  Pain typically goes away after a few hours. Pain is dose-dependent. If a small dose of prostaglandin does not cause pain, a higher dose might cause penile pain.  For men who experience pain with alprostadil, the medication is usually changed to Bimix or Trimix.

Additional risks of injectable medications are priapism (an erection that lasts more than 3-4 hours). Should an erection last more than 3-4 hours, the patient needs to go to the nearest emergency room for treatment.  Typically, the first few doses of these medications are administered in our office and the patient is observed; the goal is to choose a dose of medication that creates a good erection that lasts under an hour.  This minimizes the risk of priapism.  We require patients to have phenylephrine injections at home to self-inject in case erections last more than 2 hours to make erections go away.  

Long-term use of penile injections is also associated with a risk of developing scarring in the penis which can lead to penile curvature, narrowing, or shortening (Peyronie’s disease).

Who is a Good Candidate for Penile Injection Therapy for ED

Penile injection therapy is a well-tolerated treatment for ED with high effectiveness.  It is appropriate for men who do not achieve desirable results with oral treatment options such as Viagra, Cialis, Levitra, and Stendra or for whom shockwave therapy for ED does not work.  

Penile injection is a good alternative for men who experience unpleasant side effects from oral medications such as sildenafil, tadalafil, and avanafil. Penile injections are also used as part of penile rehabilitation therapy after radical prostatectomy.  Men for whom penile injection therapy does not work or they are unwilling to self-inject can be effectively treated with a penile implant.

Please read important considerations about penile injection therapy. Learn about other treatment options for impotence in men.

Read answers to common questions about penile injections, considerations when traveling with Trimix, and the logistics of penile injections.

Where to Get Treatment for ED in NYC?

At New York Urology Specialists, we offer specialized treatment for ED for men. Same-day appointments are available.

Call/text today: 1-646-663-5211 or make an appointment online.  

We treat sexual and erection problems and offer comprehensive STD testing for infections.  We treat penile problems in men, including phimosis, balanitis, penile irritation, and penile redness. We perform a no-scalpel vasectomy, vasectomy reversal, cosmetic circumcision, circumcision revision, penile frenuloplasty. We offer confidential appointments.

Our prices are ED treatment prices are affordable with or without insuranceLow-cost Viagra (sildenafil) and Cialis (tadalafil) are available to our patients.  We offer free insurance verification.

Read Real Stories of Men who Underwent Treatment for ED at New York Urology Specialists.

We offer ED treatment to patients within driving distance to our offices as well as from other states and countries.  Our patients come from New York, New Jersey, Pennsylvania, and Connecticut, and over 30 countries worldwide.

What do Penile Problems Look Like?

You can find pictures of penile problems including before and after treatment images in our image gallery.

What You Need to Know:

Why Choose New York Urology Specialists for Treatment of Erectile Dysfunction?

  • All treatment is performed by a board-certified urologist experienced in treating men with symptoms of ED, premature ejaculation, and other sexual problems using medical therapy, minimally invasive therapies, lasers, and surgery.
  • We are one of the few practices in the region to offer a full range of options for the treatment of sexual, and erection problems in men.
  • We offer diagnostic testing in our office, which avoids hospital costs.
  • Extensive Experience: Thousands of men have been treated successfully using medical therapy, shockwave therapy for ED, penile injections with Trimix, and penile implant surgery.
  • Confidential and Understanding Care. We understand that most of our patients desire privacy.  We see patients with a variety of urological problems. Your reason for visiting us is entirely confidential.
  • We are one of the few practices in the region to offer a full range of options for the treatment of sexual and erection problems in men.
  • We are conveniently located within a 30-60 minute commute to men who are seeking ED treatment in Manhattan, Brooklyn, Queens, Staten Island, Westchester, Long Island, Bronx, and New Jersey.

Scheduling Appointments for ED Treatment at New York Urology Specialists

If you have any questions, to schedule a consultation, please contact us or call/text: 1-646-663-5211.

We have excellent reviews from patients and their partners.  Information for out-of-state and international patients.  Find out our office hours or directions to our office

We offer affordable prices with or without insurance.  Low-cost Viagra (sildenafil) and Cialis (tadalafil) are available to our patients.

We offer weekday, weekend, and evening office hours.

Dr. Alex Shteynshlyuger is a board-certified urologist, who specializes in all aspects of care for sexual problems in men including ED, premature ejaculation, and other sexual concerns.  He has successfully treated hundreds of men with sexual problems including ED and poor libido.

Patients Reviews

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Urology by Alan on Jul 04, 2022Dr. Alex and all members of his staff are very attentive and professional. They are always willing to adjust to patient requests regarding scheduling and time. I’ve never had a negative experience when visiting the office and would highly recommend Dr. Alex and staff!


Circumcision and vasectomy by Hector Nieves on Feb 22, 2022Todo muy bien con el personal, la cirugia, el seguimiento, etc. Lo unico que podria decir un poquito negativo es el tiempo de espera despues de la hora de la cita fue bastante, pero con relacion a todo lo demas es excelente.


Review by Armando Santos on Dec 16, 2021Great experience

best urology doctor by Winston – via on Feb 14, 2021Dr Alex Shteynshlyuger is the best urology doctor there is. He is attentive, analytical, knowledgeable and skillful. Very confidential with a masterfully professional staff. I would not hesitate in recommending Dr Shteynshlyuger to the world because I am a satisfied patient of his.

solved my problem with ED by via on Jan 29, 2021Dr. Shteynshlyuger helped to solve my problem with ED

100% perfect circumcision by via on Jan 21, 2021Dr. Shteynshlyuger did what I would call an 100% perfect circumcision on me. I can’t even find my scar. He cut the precise right amount of skin. I now feel extremely happy, confident, and proud of how it looks. I am 100% satisfied with my results and I would recommend him to any guy seeking an adult circumcision. I healed in 5.5 weeks but his recommendation is 6 weeks to heal so that means zero “activity” for 6 weeks to avoid damaging the stitching. The surgical glue I pulled off at 5.5 weeks. It is important to not remove it before! The lower posterior of my shaft did not look good at first, especially w/ the surgical glue on it, but over weeks it looked better and better w/ the final results by 5.5-6 weeks being excellent When the doctor injected the anesthetic, it was painful since he must inject it deep ~6-8times. During the surgery my discomfort was maybe a 1/10, so tolerable. Make sure to buy lots of bandages/gauze before/after for daily change for 5-6 weeks

What went well

Appointment scheduling Office environment Staff friendliness Appointment wasn’t rushed Listened & answered questions Explained conditions well Trusted the provider’s decisions

What could be improved

Long wait times 

Very Pleased by A. Pereira via on Jan 21, 2021Very Pleased, I couldn’t have asked for more from Dr. S as well as everyone in the office, The procedure and after was a dream with Dr. S. If you are on the fence, I can tell you, that you will love your experience with Dr. S


treatment from New York Urology by Anthony via on Jan 07, 2021My problem with ED is gone with my treatment from New York Urology!

What went well

Appointment scheduling Office environment Staff friendliness Wait times Appointment wasn’t rushed Listened & answered questions Explained conditions well Trusted the provider’s decisions

What could be improved


recommend Dr. Shteynshlyuger by via on Jan 04, 2021Yes I would recommend Dr. Shteynshlyuger . Effective physician at all levels.

finally able to enjoy life again by Josh via on Dec 16, 2020Dr. Alex absolutely changed my life and restored my faith in doctors. When my condition first started I saw four different urologists over a period of about 6 months. All four either laughed me out of their office saying there’s nothing they could do to help, that my pain was normal, or prescribed me something that did not help or made everything worse. I prepared to live my life (22 years old now) with chronic pain that made participating in every day activities extremely difficult. Finally after getting the courage to start looking for new doctors again I found Dr. Alex Shteynshlyuger and decided to give his office a call. I proceeded to see him shortly after my call, and now a few visits and months later I am finally able to enjoy life again. Dr. Alex took the time to do the tests that other doctors did not even mention. He took different approaches, gave well explained answers to all of my questions, and made me feel like there are some doctors who really do care. On top of all of that he has some of the most helpful and kind staff I have come across. I cannot stress enough how thankful I am for Dr. Alex!

No pain at all by Elson via on Nov 25, 2020This was a very fast and easy process. No pain at all and the job was very well done. He stays on top of your progress and helps to heal faster. I will definitely recommend Dr Alex at all times!!!

Great place by Yannis via on Nov 09, 2020Very friendly staff, A great experience from the front desk to seeing the doctor. Dr.Shteynshlyuger is very professional and makes you comfortable when you’re in the room. He answers every question with detail. Great place..

I would highly recommend it to anyone by Javier – Via on Oct 11, 2020I saw the reviews about this place and was very hesitant to go but something was telling me to go with them and I don’t regret it at all, the doctor did a great job and helped me understand the process plus the staff was amazing I would highly recommend it to anyone! quick story after the procedure I was in soo much pain and called the office on a SUNDAY, the doctor gave me a call back within 15 minutes and prescribed a stronger medication, to me that meant a lot for the doctor to take time from his day on a Sunday to help me.

highly qualified diagnostician by Vladimir via on Sep 23, 2020I have been observed by Dr. Alex for many years and I must say that he is a highly qualified diagnostician, and also several times I have received qualified microsurgical assistance and very useful advice. The only reason I put 4 with a plus is a somewhat long wait for the reception.

successful procedure by Grant via on Aug 20, 2020To Dr. Shteynshlyuger and your assistants and aids, thank you guys for a successful procedure. I’d refer you to others for your compassionate, knowledgeable, attentive service and indepth follow up care.

I am very happy with this doctor. by Maria via on Aug 12, 2020I am very happy with this doctor. He is very patient and he understood all my problems. He also answered my questions and gave me some good advice.

very friendly staff by via on Apr 12, 2020excellent doctor and all very friendly staff

2 years free of any UTI by Lucretia via on Apr 09, 2020This urologist has helped me for my constant UTI’s He gave me a few tests, diagnosed the problem and now I’m 2 years free if any UTI. A kind, intelligent, caring doctor LucretiaLaMura

Doctor Shteynshlyuger provided me with the care I needed by Christopher via on Mar 11, 2020The staff is very professional. Doctor Shteynshlyuger provided me with the care I needed. The wait, visits, and instructions were brief. I followed his instructions and my issue was resolved. As a patient exercise patience. Follow the instructions and be honest about your condition and what you hope to accomplish be visiting. Thanks again Doctor.

Patient review by Jose A La Luz on Jan 24, 2020 

Buen doctor by Marcos perez on Jan 14, 2020Muy buen doctor. Y sobre todo el personal muy amable se preocupan por uno buen servicio

Thank you for your hlep by Ron on Dec 10, 2019Amazing doctor and staff. Thank you!

Shang Ring circumcision by via on Oct 29, 2019Overall, it was a good experience. Dr. Shteynshlyuger (Dr. Alex) was very nice, warm and helpful. He performed a Shang Ring circumcision for me and the procedure went well. I’m pleased with the results and there were no complications. If anyone is interested in the shang ring circumcision in the tristate area, then I’d recommend him. The whole procedure is $1850, which includes the initial consultation (provided that ther are no complications) and every follow up visit up to six months.

What went well

Appointment scheduling Office environment Staff friendliness Wait times Appointment wasn’t rushed Listened & answered questions Explained conditions well Trusted the provider’s decisions

What could be improved


Thank you doc !!! by via on Aug 14, 2019Great doctor, good bedside manner and always felt comfortable talking to him and the staff. Great location and affordable prices. Thank you doc !!!

What went well

Appointment scheduling Office environment Staff friendliness Appointment wasn’t rushed Listened & answered questions Explained conditions well Trusted the provider’s decisions 

Office very convenient location by via on Aug 13, 2019Office very convenient location Don’t have to wait for long Staff very friendly Dr shteynshyuer very experienced I had my serviced done in 3 visits now I feel good now Than you Dr. shteynhlyuger

positive experience by via on Aug 09, 2019Dr. Shteynshlyuger is professional, knowledgeable, and experienced. I had a positive experience with him.

Peronis Disease by Robert Clarke on Aug 04, 2019Dr Alex was both knowledgeable and concise with his diagnosis and advice which was well received. Dr was her knowledgeable in the subject and provided good advice.

Review by Jim on Jul 26, 2019The staff are very friendly and efficient. Appointment ease is excellent. Dr. S. is terrific diagnostician, answers your questions quickly tries to assess how you are doing and focus on the purpose(s) of our visit Treatment alternatives are discussed . The longer you are a patient, the better the experience is.

3P Removal by Karl Henry on Jul 24, 2019Went to get my penile papule remove. Got done same day, it was fast, great staff, and most importantly, pleased with the result.

Recommendation by JOHN on Jul 18, 2019Therefore I would like to recommend you to anyone who need your services.

Urology Visit by Oliver on Jul 18, 2019Staff were all very welcoming. Dr. Alex Shteynshlyuger was very knowledgeable and attentive during my time spent with him.

Outstanding by Allan B. on Jul 09, 2019Went in for a procedure with Dr. Alex and he was very calm and thorough about the the operation and the recovery. From the front desk to his assistants, everyone was very courteous, professional and polite. I highly recommend NY Urologist Specialist. They are outstanding!!!

Dr. Alex Shteynshlyuger MD
33 W 46th St 5TH FL, New York, NY

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Kyle Harris

2 months ago

ED is Treatable in Nearly Every Man

Excellence-Urology_Care-banner2At New York Urology Specialists, our urologists are specially trained in the evaluation and treatment of erectile dysfunction.  We understand the challenges that ED creates for our patients, their relationships, and their self-esteem.  We help you find a treatment for erectile dysfunction that fits your needs, lifestyle, and your preferences.

Urologists are doctors specializing in the treatment of men with erectile dysfunction. By virtue of our experience and skill, we are able to offer an effective treatment option for nearly every man who desires an effective treatment for ED.  We offer medical and surgical treatment for erectile dysfunction.

We Treat Some of the Most Complex ED Problems Including:

Schedule an Appointment with Dr. Shteynshlyuger:

Call/text today: 1-646-663-5211 or make an appointment online

Dr. Alex Shteynshlyuger is a fellowship-trained board-certified urologist with expertise in the evaluation and treatment of sexual and erection problems in men using modern, effective, and proven treatment methods.  We offer inflatable penile implant, shockwave therapy for ED, and treatment for Peyronie’s disease.

He is highly recommended by top primary care physicians in the New York area. If you or someone you know has been experiencing urological symptoms, make an appointment to take advantage of Dr. Shteynshlyuger’s expert advice. Please feel free to contact us with any questions.

If you have any questions, to schedule a consultation, please contact us or call/text: 1-646-663-5211.

We have excellent reviews from patients and their partners.  Information for out-of-state and international patients.  Find out our office hours or directions to our office

We offer affordable appointment prices with or without insurance.  Low-cost Viagra (sildenafil) and Cialis (tadalafil) are available to our patients.

We offer weekday, weekend, and evening office hours.


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